Open-source model

The IPECAD Alzheimer’s disease model (Green et al, 2019) has been developed by the IPECAD Modelling Group as a framework to model disease progression across Alzheimer’s disease (AD) and to assess the costs and outcomes associated with the condition, and the cost-effectiveness of interventions for people affected by AD, using the scenario of a future disease modifying therapies (DMT) for people with mild cognitive impairment (MCI) due to AD.

A description of the model (version 1.0) is published open-access in the journal Alzheimer’s and Dementia: the journal of the Alzheimer’s Association. DOI:doi1234567890. LINK

You can use this open-source model for free under the Creative Commons Attribution-ShareAlike 4.0 International Public License.

We host a version history developed by the IPECAD Modelling Group below.

We provide a listing of self-reported external applications of the model below to endorse transparency.

Request a download link


External applications

none yet

Version history

Version 1.0

Modelling group

left to right: Bengt Winblad, Colin Green, Ron Handels, Anders Wimo, Anders Sköldunger, Anders Gustavsson, Linus Jönsson

Anders Gustavsson (Karolinska Institutet, Sweden)

Colin Green (University of Exeter, UK)

Ron Handels (Karolinska Institutet, Sweden; Maastricht University, Netherlands)

Gunilla Johansson (Karolinska Institutet, Sweden)

Linus Jönsson (Karolinska Institutet, Sweden)

Anders Sköldunger (Karolinska Institutet, Sweden)

Anders Wimo (Karolinska Institutet, Sweden)

Bengt Winblad (Karolinska Institutet, Sweden)

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